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American Society of Microbiology ABMM Sample Questions:
1. A patient who received a solid organ transplant develops a pneumonia. Bronchoalveolar lavage fluid is positive for a single-stranded RNA virus that can cause giant cell formation with intranuclear and intracytoplasmic inclusions. The MOST likely causative agent is:
A) Parainfluenza virus
B) Human metapneumovirus
C) Adenovirus
D) Respiratory syncytial virus (RSV)
2. A patient develops a febrile illness with jaundice and dark urine after receiving a blood transfusion.
Laboratory testing reveals an elevated level of unconjugated bilirubin and a positive direct Coombs test.
Serological testing is positive for antibodies against a protozoan parasite that infects erythrocytes. The MOST likely causative agent is:
A) Trypanosoma cruzi
B) Plasmodium falciparum
C) Toxoplasma gondii
D) Babesia microti
3. A patient with a history of recurrent sinusitis and bronchitis is diagnosed with cystic fibrosis. Sputum cultures repeatedly grow a Gram-negative rod that is oxidase-positive and produces a blue-green pigment. This organism's chronic colonization of the respiratory tract in cystic fibrosis patients is primarily due to its ability to:
A) Produce potent exotoxins that damage the ciliated epithelium.
B) Form a biofilm that protects it from host defenses and antibiotics.
C) Evade phagocytosis by alveolar macrophages through capsule production.
D) Exhibit rapid intracellular replication within respiratory epithelial cells.
4. A foodborne outbreak is suspected after several individuals who attended a potluck dinner develop nausea, vomiting, and abdominal cramps within 1-6 hours of eating. No fever or diarrhea is reported. The MOST likely bacterial toxin involved is:
A) Shiga toxin
B) Clostridium perfringens enterotoxin
C) Botulinum toxin
D) Staphylococcal enterotoxin
5. Lyme disease, characterized initially by erythema migrans, is caused by Borrelia burgdorferi. What is the primary arthropod vector responsible for transmitting this spirochete to humans in the Northeastern United States?
A) Pulex irritans (Human flea)
B) Dermacentor variabilis (American dog tick)
C) Amblyomma americanum (Lone Star tick)
D) Ixodes scapularis (Blacklegged tick)
Solutions:
| Question # 1 Answer: A | Question # 2 Answer: D | Question # 3 Answer: B | Question # 4 Answer: D | Question # 5 Answer: D |
By Astrid
